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Rectal Carcinoma, Mayo Hospital Experience

机译:直肠癌,梅奥医院经验

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For patients having rectal carcinoma, resection offers the only chance of cure. The approach to operation is influenced by the finding at sigmoidoscopy, degree of fixity of the growth as assessed by rectal examination and the histology of the tumor. In the study different operative option according to the site of tumor and demographic aspect of the rectal carcinoma in local community were studied. It is a prospective study carried out at Mayo Hospital, Lahore Pakistan to assist in the development of the management guideline. In this study, 50 patients with new diagnosis of carcinoma rectum were included. Out of the 50 patients 44% had tumor of the upper rectum 16% in the middle and 40% in the lower rectum. In 96% of the cases histology was adenocarcinoma and 2% each for melanoma and lymphoma. Resection of the primary disease in 92% of the cases, 20% of the cases presented with acute obstruction and 4% of the cases were inoperable. Curative resection was possible in 80% of the cases, palliation was achieved in 12% cases and 4% of the cases deemed inoperable at the time of operation. Incidence of rectal carcinoma is higher in younger age group being < 40 and resection of the primary tumor is the cure in early cases.
机译:对于直肠癌患者,切除是唯一治愈的机会。手术方法受到乙状结肠镜检查的发现,通过直肠检查评估的生长固定程度和肿瘤组织学的影响。在研究中,根据肿瘤的部位和直肠癌的人口统计学特征,对不同的手术选择进行了研究。这是在巴基斯坦拉合尔市梅奥医院进行的一项前瞻性研究,以协助制定管理指南。在这项研究中,包括50例新诊断为直肠癌的患者。在50名患者中,有44%的患者患有上直肠肿瘤,中部肿瘤为16%,下直肠肿瘤为40%。在96%的病例中,组织学是腺癌,黑色素瘤和淋巴瘤各占2%。切除原发疾病的病例为92%,急性梗阻的病例为20%,无法手术的病例为4%。在80%的病例中可以进行根治性切除,在手术时12%的病例和4%不能手术的病例中实现了姑息性切除。年龄小于40岁的年轻人中直肠癌的发病率更高,早期切除肿瘤是可以治愈的。

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