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首页> 外文期刊>Asian Journal of Pharmaceutical and Clinical Research >ASSESS PREDIABETES RISK, AS A GOLDEN PERIOD FOR PREVENTION OF DIABETES
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ASSESS PREDIABETES RISK, AS A GOLDEN PERIOD FOR PREVENTION OF DIABETES

机译:评估糖尿病前期风险,作为预防糖尿病的黄金期

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摘要

Objective: Prediabetes is a high-risk condition for diabetes development and several other health outcomes later in life, but little is known about the factors associated with this condition. On the other hand, by predicting the risk of prediabetes, it is also a golden period for prevent or delay the diabetes conversion. The aim here was to assess the prevalence, risk factor that associated, and build a model to assess prediabetes risk. Methods: A cross-sectional study was conducted in Palembang, Indonesia. Data were collected during January until May 2016. We recruited adult age >15 years from 16 districts in Palembang. Anthropometric, demographic, and clinical history data were measured by standard methods. Capillary blood glucose was measured by finger prick test, followed by confirmatory oral glucose tolerance tests. Results: Of a total of 1241 participants, the prevalence of prediabetes was 27.8% (345 participants) and 72.2% (896 participants) and those were normal blood glucose. Employment, age, exercise, alcohol consumption, body mass index, systolic pressure, diastolic pressure, waist circumference, and hypercholesterol history were screened out as independent factors to build the prediction risk model. Conclusion: The prediabetes prediction model can be used easily and understood by health-related users to assess prediabetes risk. The intervention program, designed based on our prediabetes model to prevent or delay the conversion of prediabetes to diabetes in the population. The discovery of pharmacological therapies to prevent further conversion is needed.
机译:目的:糖尿病前期是糖尿病发展和其他一些健康后果的高风险疾病,但对该病相关的因素知之甚少。另一方面,通过预测前驱糖尿病的风险,这也是预防或延缓糖尿病转化的黄金时期。此处的目的是评估患病率,相关的危险因素,并建立模型来评估糖尿病前期风险。方法:在印度尼西亚的巨港进行了横断面研究。在1月至2016年5月期间收集了数据。我们从巨港的16个地区招募了15岁以上的成年人。人体测量学,人口统计学和临床​​病史数据通过标准方法进行测量。通过手指点刺试验测量毛细管血糖,然后进行口服葡萄糖耐量试验。结果:在总共1241名参与者中,糖尿病前期的患病率为27.8%(345名参与者)和72.2%(896名参与者),并且血糖水平正常。筛选出就业,年龄,运动,饮酒,体重指数,收缩压,舒张压,腰围和高胆固醇史作为独立因素,以建立预测风险模型。结论:糖尿病前期预测模型可以轻松使用,并由健康相关用户理解,以评估糖尿病前期风险。根据我们的糖尿病前期模型设计的干预计划,旨在防止或延迟人群中糖尿病前期向糖尿病的转化。需要发现防止进一步转化的药理疗法。

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