ACUTE AND SUBACUTE TOXICITY STUDIES OF ETHANOLIC EXTRACT OF ACALYPHA INDICA Linn IN MALE WISTAR ALBINO RATS

摘要

The aim of the present study was to evaluate acute and sub acute toxicity of the ethanolic extract of Acalyphaindica on male wistar rats at the dose levels of 100,200,300,400, and 500mg/kg b.w.) at a rate of 1.0ml /rat/day to different sets of animal for 30 days Results from the present study have elucidated that treatment of A.Indica exerts no significant signs of toxicity at any dose level used in the study. Physical, biochemical as well as hematological parameters was unaltered throughout the study. The results of study have suggested there was no obvious toxicity observed with the treatment of A.Indica. It was found to be safe alternative for various severe infections.