Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption

K Redlich; S Hayer; CR Dunstan; M Tohidast-Akrad; S Lang; G Kollias; G Steiner; JS Smolen; G Schett

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Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption

机译：骨保护蛋白和双膦酸盐对破骨细胞的靶向治疗导致TNFα介导的骨吸收减少

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来源
《Arthritis Research 》 |2001年第1期| 共页
作者
K Redlich; S Hayer; CR Dunstan; M Tohidast-Akrad; S Lang; G Kollias; G Steiner; JS Smolen; G Schett;
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中图分类医药、卫生 ;
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1. RNA therapeutics targeting osteoclast-mediated excessive bone resorption [J] . WangY., GraingerD.W. Advanced drug delivery reviews . 2012 ,第12期

机译：针对破骨细胞介导的过度骨吸收的RNA治疗药物
2. Osteoprotegerin inhibit osteoclast differentiation and bone resorption by enhancing autophagy via AMPK/mTOR/p70S6K signaling pathway in vitro [J] . Tong Xishuai, Gu Jianhong, Song Ruilong, Journal of cellular biochemistry. . 2019 ,第2期

机译：骨蛋白酶通过在体外通过AMPK / MTOR / P70S6K信号通路增强自噬抑制破骨细胞分化和骨吸收
3. Inhibition of osteoclast bone resorption activity through osteoprotegerin-induced damage of the sealing zone [J] . SongRuilong, GuJianhong, LiuXuezhong, International journal of molecular medicine . 2014 ,第3期

机译：通过骨保护素诱导的密封区破坏来抑制破骨细胞的骨吸收活性
4. The mechanism for early promotion of guided bone regeneration with strontium-doped hydroxyapatite bone substitute involves a reduction of osteoclasts and osteoblast-osteoclast coupling processes [C] . Ibrahim Elgali, Alberto Turri, Wei Xia, World biomaterials congress . 2016

机译：用锶掺杂的羟基磷灰石替代骨早期促进引导性骨再生的机制涉及减少破骨细胞和成骨细胞-破骨细胞的偶联过程
5. Epimedium Active Component Icaritin Enhances Bone Mass through Regulating the Coupling of Bone Formation and Resorption Mediated by Distinct Signaling Targets [D] . Lu, Li. 2016

机译：淫羊med活性成分伊立肽通过调节不同信号靶标介导的骨形成和吸收的耦合来增强骨量。
6. Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption [O] . K Redlich, S Hayer, CR Dunstan, 2001

机译：骨保护蛋白和双膦酸盐对破骨细胞的靶向治疗导致TNFα介导的骨吸收减少
7. Osteoprotegerin influences the bone resorption activity of osteoclasts [O] . YING-XIAO FU, JIAN-HONG GU, YI-RAN ZHANG, 2013

机译：骨盆蛋白影响破骨细胞的骨吸收活性
8. Identification of Leukocyte Subpopulations Responsible for the Production of Osteoclast Activating Factor and their Role in Bone Resorption [R] . Hawley, C. E. 1980

机译：鉴定负责破骨细胞活化因子产生的白细胞亚群及其在骨吸收中的作用

Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption

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