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Ceramic nanoparticles: Recompense, cellular uptake and toxicity concerns

机译:陶瓷纳米颗粒:补偿,细胞摄取和毒性问题

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Abstract Over the past few years, nanoparticles and their role in drug delivery have been the centre of attraction as new drug delivery systems. Various forms of nanosystems have been designed, such as nanoclays, scaffolds and nanotubes, having numerous applications in areas such as drug loading, target cell uptake, bioassay and imaging. The present study discusses various types of nanoparticles, with special emphasis on ceramic nanocarriers. Ceramic materials have high mechanical strength, good body response and low or non-existing biodegradability. In this article, the various aspects concerning ceramic nanoparticles, such as their advantages over other systems, their cellular uptake and toxicity concerns are discussed in detail.
机译:摘要在过去的几年中,纳米颗粒及其在药物输送中的作用一直是吸引人们关注的新型药物输送系统的中心。已经设计了各种形式的纳米系统,例如纳米粘土,支架和纳米管,在诸如载药量,靶细胞摄取,生物测定和成像等领域具有许多应用。本研究讨论了各种类型的纳米颗粒,特别着重于陶瓷纳米载体。陶瓷材料具有较高的机械强度,良好的机体响应性以及较低或不存在的生物降解性。在本文中,详细讨论了涉及陶瓷纳米粒子的各个方面,例如它们相对于其他系统的优势,它们对细胞的吸收和毒性问题。

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