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Retrograde balloon dilation 10weeks after renal transplantation for transplant ureter stenosis – our experience and review of the literature

机译:肾移植后10周逆行球囊扩张治疗输尿管狭窄–我们的经验和文献复习

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Objective Despite many efforts to prevent ureteric stenosis in a transplanted kidney, this complication occurs in 3–5% of renal transplant recipients. Balloon dilatation (BD) is a possible minimally invasive approach for treatment, but reports to date refer only to the antegrade approach; we analysed our experience with retrograde BD (RBD) and reviewed previous reports. Patients and methods From October 2008 to February 2011, eight patients after renal transplantation (RTX) underwent RBD for transplant ureteric stenosis at our hospital. We retrospectively analysed the outcome and reviewed previous reports. Results The eight recipients (five men and three women; median age 55years, range 38–69) were treated with one or two RBDs for transplant ureteric stenosis. There were no complications. The median (range) time after RTX was 4.5 (2.5–11)months. Long-term success was only achieved in one recipient, while five patients were re-operated on (three with a new implant, two by replacement of transplanted ureter with ileum) after a median (range) of 2.8 (0.7–7.0)months after unsuccessful RBD(s). For two recipients the success remained unclear (one graft loss due to other reasons, one result pending). When the first RBD was unsuccessful there was no improvement with a second. Conclusion RBD is technically feasible, but our findings and the review of previous reports on antegrade ureteric dilatation suggest that the success rate is low when the ureter is dilated at ?10weeks after RTX. From our results we cannot recommend RBD for transplant ureteric stenosis at ?10weeks after RTX, while previous reports show favourable results of antegrade BD in the initial 3months after RTX.
机译:目的尽管为预防移植肾中的输尿管狭窄做出了许多努力,但这种并发症发生在3–5%的肾移植受者中。球囊扩张术(BD)是一种可能的微创治疗方法,但迄今为止的报道仅涉及顺行性治疗。我们分析了逆行BD(RBD)的经验,并回顾了以前的报告。患者与方法从2008年10月至2011年2月,我院对8例肾移植手术(RTX)进行了RBD的输尿管狭窄患者。我们回顾性分析结果并回顾了以前的报告。结果对八名接受者(五名男性和三名女性;中位年龄55岁,范围38-69)进行了一或两个RBD治疗移植输尿管狭窄。没有并发症。 RTX之后的中位(范围)时间为4.5(2.5-11)个月。仅在一名接受者上获得了长期成功,而中位(范围)为2.8(0.7-7.0)个月后,有五名患者再次手术(三名新植入物,两名通过回肠置换移植输尿管)再次手术。 RBD不成功。对于两名接受者而言,成功率尚不清楚(一项因其他原因导致的移植物丢失,一项结果待定)。当第一个RBD不成功时,第二个则没有任何改善。结论RBD在技术上是可行的,但是我们的发现和先前有关顺行输尿管扩张的报告的回顾表明,在RTX术后10周内扩张输尿管时,成功率很低。根据我们的结果,我们不能建议RBD在RTX术后10周内用于移植输尿管狭窄,而先前的报道显示RTX术后最初3个月前顺行BD的效果良好。

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