Mesoporous alumina as a solid phase extraction adsorbent for the determination of abamectin and ivermectin in vegetables by liquid chromatography-tandem mass spectrometry

摘要

We report the synthesis of mesoporous alumina by a template method and its applications as a new solid phase extraction adsorbent with abamectin and ivermectin as the target analytes by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Chromatographic separation was conducted on a C18 column using a gradient mobile phase consisting of methanol (solvent A) and 0.2% formic acid in a 5 mmol La?’1 ammonium acetate buffer (solvent B) at a flow rate of 0.3 mL mina?’1. The linearity of the calibration curves was excellent and yielded correlation coefficients (r2 = 0.9990a€“0.9999) in a range of 0.02a€“0.50 mg La?’1. Samples were spiked with known quantities of the analytes at three different concentration levels (0.05, 0.10 and 0.20 mg La?’1), and the recoveries were in the range of 87.3a€“104.5% with the relative standard deviation (RSD) values ranging between 0.53% and 5.8%. The limits of detections and limits of quantization were 0.16 ng ga?’1 and 0.53 ng ga?’1, respectively. These results indicated that mesoporous alumina has enormous potential as a novel solid phase extraction adsorbent material in the food security field.