A Case of Acute Lymphoblastic Leukemia with dic(9;12) and Additional Trisomy 8

摘要

Background :A 16-year-old boy was diagnosed with acute lymphoblastic leukemia with dic(9;12). Physical examination revealed cervical lymphadenopathy and splenomegaly. Hemoglobin was 5.1 g/dL, WBC was 4,400/ L and the platelet count was 3,000/ L. Immunophenotyping showed positivity of WBC was 4,400/ L and the platelet count was 3,000/ L. Immunophenotyping showed positivity of HLA-DR, CD34, CD10, CD19, CD20, and CD22. The chromosome analysis of bone marrow aspirate showed 46,XY,+8,dic(9;12)(p11-13;p11-12). There has been a complete remission by induction chemotherapy as of the 62nd day.