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Predictors of successful non-operative management of grade III & IV blunt pancreatic trauma

机译:非手术治疗成功治疗III和IV级钝性胰腺创伤的预测因素

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Introduction Although surgery is the preferred treatment for grade III&IV pancreatic trauma, there is a growing movement for non-operative management. in blunt pancreatic trauma. Very few studies compare operative versus non-operative management in adult patients. Methods Retrospective analysis of a prospectively maintained database was performed from 2004 to 2013 in the department of gastrointestinal surgery, NIMS, Hyderabad. Comparative analysis was performed between patients who failed versus those who were successfully managed with non-operative management. Results 34 patients had grade III/IV trauma out of which 8 were operated early with the remaining 26 initially under a NOM strategy, 10 of them could be successfully managed without any operation. Post-traumatic pancreatitis, Necrotizing pancreatitis, Ileus, contusion on CT, surrounding organ injuries are independently associated with failure of NOM on a univariate analysis. On multivariate logistic regression presence of necrosis& associated organ injury are factors that predict failure of NOM independently. Development of a pseudocyst is the only significant factor that is associated with a success of NOM. Conclusions Non-operative measures should be attempted in a select group of grade III&IV blunt pancreatic trauma. In hemodynamically stable patients with a controlled leak walled off as a pseudocyst without associated organ injuries and pancreatic necrosis, NOM has a higher success rate. Highlights ? Non-operative measures should be attempted in a select group of high grade (grade III/IV) pancreatic trauma. ? Controlled leak walled off as a pseudocyst, absent necrosis&organ injuries predict high success rate for NOM. ? Dedicated nutritional, gastrointestinal and interventional radiological support are the key components of care.
机译:引言尽管外科手术是Ⅲ,Ⅳ级胰腺外伤的首选治疗方法,但非手术治疗的趋势正在不断发展。在钝性胰腺创伤中。很少有研究比较成年患者的手术治疗与非手术治疗。方法对2004年至2013年在海德拉巴NIMS胃肠外科进行的前瞻性维护数据库进行回顾性分析。失败患者与非手术治疗成功患者之间进行了比较分析。结果34例具有III / IV级创伤的患者,其中8例早期手术,其余26例最初采用NOM策略,其中10例无需任何手术即可成功治疗。单因素分析显示,创伤后胰腺炎,坏死性胰腺炎,肠梗阻,CT挫伤,周围器官损伤均与NOM失败相关。在多因素逻辑回归分析中,坏死和相关器官损伤的存在是独立预测NOM失败的因素。假性囊肿的发展是与NOM成功相关的唯一重要因素。结论Ⅲ,Ⅳ级钝性胰腺外伤应选择非手术措施。在血液动力学稳定的患者中,假性囊肿被控制在渗漏状态而没有相关器官损伤和胰腺坏死,NOM的成功率更高。强调 ?某些高级别(III / IV级)胰腺创伤患者应尝试非手术措施。 ?可控的渗漏被当作假性囊肿,没有坏死和器官损伤预示着NOM的成功率很高。 ?专门的营养,胃肠道和介入放射学支持是护理的关键组成部分。

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