Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

Dao-Fu Dai; Tony Chen; Jonathan Wanagat; Michael Laflamme; David J. Marcinek; Mary J Emond; Calvin P. Ngo; Tomas A. Prolla; Peter S. Rabinovitch

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Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

机译：线粒体突变小鼠的年龄依赖性心肌病通过靶向线粒体的过氧化氢酶的过表达而减弱

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Mitochondrial defects have been found in aging and several age-related diseases. Mice with a homozygous mutation in the exonuclease encoding domain of mitochondrial DNA polymerase gamma (Polg

机译：在衰老和几种与年龄有关的疾病中发现了线粒体缺陷。线粒体DNA聚合酶γ（Polg

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《Aging cell.》 |2010年第4期|共9页
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Dao-Fu Dai; Tony Chen; Jonathan Wanagat; Michael Laflamme; David J. Marcinek; Mary J Emond; Calvin P. Ngo; Tomas A. Prolla; Peter S. Rabinovitch;
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中图分类细胞生物学;
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1. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. [J] . Dai DF, Chen T, Wanagat J, Aging cell. . 2010,第4期

机译：线粒体突变小鼠的年龄依赖性心肌病通过靶向线粒体的过氧化氢酶的过表达而减弱。
2. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria [J] . Dao-Fu Dai, Tony Chen, Jonathan Wanagat, Aging Cell . 2010,第4期

机译：线粒体突变小鼠的年龄依赖性心肌病被针对线粒体的过氧化氢酶的过表达减弱
3. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. [J] . Dai DF, Chen T, Wanagat J, Aging cell. . 2010,第4期

机译：在线粒体突变小鼠中依赖于依赖性的心肌病，通过靶向线粒体的过度表达抑制。
4. OVEREXPRESSION OF THE MITOCHONDRIAL PYRUVATE CARRIER INCREASES CHO CELL AND RECOMBINANT PROTEIN PRODUCTIVITY AND REDUCES LACTATE PRODUCTION [C] . Dubhe B. Bulte, Carolina Gomez, Laura A. Palomares, Cell culture engineering conference . 2018

机译：线粒体丙酮酸载体的过表达增加了CHO细胞和重组蛋白的生产力，并减少了乳酸的生产
5. Longevity and stress resistance conferred by targeted overexpression of mitochondrial Drosophila peroxiredoxin mtDPX (thioredoxin peroxidase Dpx-5037) in Drosophila melanogaster [D] . Niu, Genying 2006

机译：线粒体果蝇过氧化物酶毒素mtDPX（硫氧还蛋白过氧化物酶Dpx-5037）的靶向过表达赋予果蝇长寿和抗逆性
6. Age-Dependent Cardiomyopathy in Mitochondrial Mutator Mice is Attenuated by Overexpression of Catalase Targeted to Mitochondria [O] . Dao-Fu Dai, Tony Chen, Jonathan Wanagat, -1

机译：通过针对线粒体的过度表达抑制线粒体突变小鼠的年龄依赖性心肌病变
7. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria [O] . Dao-Fu Dai, Tony Chen, Jonathan Wanagat, 2010

机译：通过针对线粒体的过度表达抑制线粒体突变小鼠的年龄依赖性心肌病变

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

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