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Sinus penetration of saline solution irrigation and atomizer in a cadaveric polyp and allergic fungal sinusitis model

机译:尸体息肉和过敏性真菌性鼻窦炎模型中盐溶液冲洗和雾化器的窦渗透

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Allergic fungal sinusitis (AFS) is a stubborn disease requiring surgical and medical management. Delivery of topical medication is paramount in these patients, but the most difficult to accomplish. We investigated heavy irrigation (nasal douche) and atomized medication delivery potential in a cadaveric sinus model of polypoid AFS disease. Three disease models were created: a control that involved unoperated sinuses and no simulated disease; an unoperated AFS with type II polyposis mode; and an operated model with recurrent allergic fungal sinusitis with type II polyposis. The maxillary sinus showed the best irrigation and overall the heavy irrigator was more efficient than the atomizer.
机译:过敏性真菌性鼻窦炎(AFS)是一种顽固性疾病,需要进行手术和医疗管理。在这些患者中,外用药物的交付是最重要的,但最难实现。我们在息肉样AFS病的尸体鼻窦模型中调查了重度冲洗(鼻腔冲洗)和雾化药物的输送潜力。建立了三种疾病模型:一种涉及未手术鼻窦且无模拟疾病的对照; II型息肉病模式的未手术AFS;复发性过敏性真菌性鼻窦炎伴Ⅱ型息肉的手术模型。上颌窦显示出最佳的冲洗效果,而总体而言,重型冲洗器比雾化器更有效。

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