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Strange Case of Kaposi's Sarcoma that Followed PRP Injection of Lesion

机译:PRP注射病灶后的卡波济肉瘤奇怪病例

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Kaposi's Sarcoma is a spindle-cell tumor thought to be derived from endothelial cell lineage. This condition carries a variable clinical course ranging from minimal mucocutaneous disease to extensive organ involvement. In Iraq, there are upsurge of cases of Kaposi's since 1991 as a result of exposure to depleted uranium in South of Iraq and South to Baghdad. We report one case of Kaposi's sarcoma in a 27 year old female with a history of face PRP injection in very early course of the disease and she presented with a nine months history of bilateral asymmetrical dusky red plaques involving the periorbital area, cheeks, followed by spread to other parts of body like chest, arms and thighs. The diagnosis was confirmed by histopathological findings on biopsy, and positive HHV-8 immunostaining. PRP injection might share in the aggressive course of Kaposi's sarcoma and its rapid spread to other parts of body.
机译:卡波济氏肉瘤是一种纺锤状细胞瘤,被认为源自内皮细胞谱系。这种疾病的临床病程从最小的粘膜皮肤病到广泛的器官受累。在伊拉克,由于暴露于伊拉克南部和南部至巴格达的贫铀,自1991年以来卡波西病例激增。我们报道了一名27岁女性卡波西肉瘤病例,该病在病程很早的时候就曾接受过面部PRP注射,她出现了9个月的双侧不对称暗红色斑块病史,涉及眶周区域,脸颊,其次是传播到身体的其他部位,如胸部,手臂和大腿。活检的组织病理学发现和HHV-8免疫染色阳性证实了诊断。 PRP注射可能会参与卡波济肉瘤的侵袭性进程,并迅速扩散到身体的其他部位。

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