Side Effects of Immunosuppressive Regimens After Renal Transplantation and Multiple-Sample Assessment of Quality of Life

摘要

Influences of the side effects and interferences of immunosuppressants on the quality of life (QOL) of renal transplant recipients have been discussed. 72 renal transplant recipients were surveyed utilizing 25-item health status questionnaires, and modified transplant symptom occurrence and symptom distress scales. The results showed that the frequencies and symptom interferences of side effect after receiving immunosuppressants were below medium level. Physical and mental health related QOL was most significantly affected by symptom occurrence and symptom distress, respectively. Besides, postoperative comorbidity, work status, age and household income have also been demonstrated to be able to predict the postoperative QOL. Side effects all occurred to various extents after receiving immunosuppressants to the renal transplant recipients, the occurrence and interference of the symptoms were not apparent, which would affect the postoperative QOL.