Effect of Ramadan fasting on glucose, glycosylated haemoglobin, insulin, lipids and proteinous concentrations in women with non-insulin dependent diabetes mellitus

摘要

The objective of this study was to investigate the effect of Ramadan fasting on body mass index (BMI)?and on certain biochemical parameters of serum?in women patients with non-insulin dependent diabetes mellitus. Sixty-six subjects from 3 regions located in the west of Algeria participated in this study. All participating patients were studied a week before Ramadan and at the third week of Ramadan fasting. No statistically significant fluctuations were noted in BMI either during Ramadan or in non-fasting days.?However, the rates of glycosylated haemoglobin (HbA1c) decreased slightly (P < 0.05) during the last week of the month of Ramadan among the diabetic patients.?Also, the glucose levels were?significantly?(p < 0.05) higher in the serum subjects of patients during the fasting period when compared to the level before Ramadan.?This could be due to the significant decrease (P < 0.05) of insulin levels in patients during the fasting period. The rates of HDL?cholesterol?recorded?in the blood?among patients rose?significantly (p < 0.05)?during the Ramadan?than during the non-fasting period.?The statistically significant increase in HDL-cholesterol explains clearly the beneficial effect of Ramadan fasting on diabetic’s serum lipids.?Moreover,?serum total cholesterol, triglyceride, LDL cholesterol and VLDL cholesterol levels decreased significantly (p