A review on phytochemistry and pharmacological effects of Trigonella foenum-graecum

摘要

Background and aims:?Fenugreek (Trigonella foenum-graecum) is a medicinal plant with potential applications in the medicinal purposes. Fenugreek has been used in food as a flavouring agent since ancient times in many countries like Greece, Rome and Egypt. It has a special place in the traditional medical system. The aim of this study was to review phytochemistry and pharmacological effects of?Trigonella foenum-graecum.Methods: This research was a review study. Data were collected using articles in various databases and books about pharmacological effects of?Trigonella foenum-graecum.Results:?The seeds are rich sources of lipids, protein, mucilage, calcium, dietary fiber B vitamins, Iron, protease inhibitors and several steroid saponins, tiny amounts of alkaloid, furostanol glycosides and steroidal peptide. As a medicinal plant, fenugreek recognized as a galactagogue or lactation stimulant in women after child birth as well as for its ability to treat wounds and sore muscles. In addition, it has the ability to be as antibacterial, anti-ulcer, anti-cancer, anthelmintic (antagonistic effect against parasitic worms), and antinociceptive (pain-reducing) properties. In recent years, laboratory studies and clinical trials have focused on the potential activity of fenugreek as a natural medicine.Conclusion:These studies have shown that fenugreek plants possess immunomodulatory, hypocholesterolaemic, hypoglycaemic, gastro- and hepatoprotective and antioxidative properties. Pharmacological properties of fenugreek have been explored to identify a role for the plant in diabetes management and in cardiovascular health, indicating the presence of bioactive compounds in fenugreek, which may be responsible for its health benefits.