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The Accuracy of Point-of-Care Creatinine Testing in the Emergency Department

机译:急诊科即时肌酐检测的准确性

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Objective.To determine the accuracy of Point-Of-Care testing (PoCT) creatinine values when compared to standard central laboratory testing (IDMS) and to demonstrate if and how a discrepancy could lead to improper risk stratification for contrast induced nephropathy (CIN).Methods.We conducted a descriptive retrospective chart review of patients seen in the Emergency Department of a single suburban, community, and academic medical center. We included patients who presented to the department between March 2013 and September 2014 who had blood samples analyzed by both PoCT and IDMS.Results.Mean IDMS creatinine values were 0.23 mg/dL higher when compared with i-Stat values. 95% of the time, the IDMS creatinine value was variable and ranged from −0.45 mg/dL to +0.91 mg/dL when compared to the i-Stat creatinine. When using i-Stat creatinine values to calculate GFR, 47 out of 156 patients had risk category variations compared to using the IDMS value. This affected 30.1% of the total eligible sample population (22.9% to 37.3% with 95% CI).Conclusion.We found a significant discrepancy between PoCT and IDMS creatinine values and found that this discrepancy could lead to improper risk stratification for CIN.
机译:目的:确定与标准中央实验室检测(IDMS)相比,即时检测(PoCT)肌酐值的准确性,并证明差异是否以及如何导致对比剂诱发肾病(CIN)的危险分层。方法:我们对郊区,社区和学术医疗中心的急诊科中的患者进行了描述性回顾性图表审查。我们纳入了2013年3月至2014年9月在科室就诊的患者,同时通过PoCT和IDMS对血液样本进行了分析。结果.IDMS肌酐平均值较i-Stat值高0.23μmg/ dL。在95%的时间中,与i-Stat肌酐相比,IDMS肌酐值是可变的,范围为-0.45 µmg / dL至+0.91 µmg / dL。当使用i-Stat肌酐值计算GFR时,与使用IDMS值相比,156名患者中有47名患者的风险类别存在差异。这影响了总合格样本人群的30.1%(CI值为95%时为22.9%至37.3%)。结论。我们发现PoCT和IDMS肌酐值之间存在显着差异,并发现该差异可能导致CIN的风险分层不当。

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