Renal function after nephron-sparing surgery for renal tumors

摘要

Nephron sparing surgery (NSS) is a technique morefrequently utilized in the case of surgical treatmentof kidney tumor. The aim of the study is to assess renalfunction in patients treated with NSS for renal tumors.Twenty patients, after NSS performed for renal tumor,were included in the study. In each patient dynamicrenal scintigraphy was performed before surgicaltreatment (test No. 1) and after a mean interval of12 months after surgical procedure (test No. 2). In eachtest renographic curves were evaluated. Creatinine levelsand GFR rates were also assessed. Mean GFR was 84 ml/min/1.73 m2 before surgery, and 79 ml/min/1.73 m2 aftersurgical procedure. Mean change of GFR value after thesurgical procedure was -5.1 (p >0.058). On renographysignificant deterioration of renal function was observedin the operated kidneys of 4 patients (20%) after NSS,insignificant deterioration - in four patients (20%) andimprovement of renal function of operated kidney wasfound in one patient. In 12 patients (60%) no changewas observed. The relative percentage GFR-share ofoperated kidney decreased by the average value of 3.8%(p >0.005). Multifactorial analysis did not identify significanteffect of potential risk factors on the functionof the kidney subjected to NSS. Preliminary results ofthis study confirm that deterioration of renal functionafter NSS is a rare event