An Experimental Design Approach to Optimization of the Liquid Chromatographic Separation Conditions for the Determination of Metformin and Glibenclamide in Pharmaceutical Formulation

Ebru C? ubuk Demiralay

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An Experimental Design Approach to Optimization of the Liquid Chromatographic Separation Conditions for the Determination of Metformin and Glibenclamide in Pharmaceutical Formulation

机译：优化药物制剂中二甲双胍和格列本脲测定液相色谱分离条件的实验设计方法

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An optimization methodology is introduced for inve stigating the retention behavior and the separation factor of met for - min, gliclazide (I.S.) and glibenclamide. This inve stigation has been focused on studying the influence of pH value of the mobile p

机译：引入了一种优化方法，以研究-min，格列齐特（I.S.）和格列本脲的残留行为和met的分离因子。该研究一直集中在研究移动式洗衣机pH值的影响。

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《Acta Chimica Slovenica》 |2012年第2期|共8页
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Ebru C? ubuk Demiralay;
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中图分类化学;
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1. An Experimental Design Approach to Optimization of the Liquid Chromatographic Separation Conditions for the Determination of Metformin and Glibenclamide in Pharmaceutical Formulation [J] . Ebru Qubuk Demiralay Acta Chimica Slovenica . 2012,第2期

机译：优化药物配方中二甲双胍和格列本脲测定液相色谱分离条件的实验设计方法
2. Comparative High-Performance Liquid Chromatographic and High-Performance Thin-Layer Chromatographic Study for the Simultaneous Determination of Dapagliflozin and Metformin Hydrochloride in Bulk and Pharmaceutical Formulation [J] . Nasser Sally, Salama Ismail, Mostafa Samia M., Journal of Planar Chromatography-Modern TLC: JPC . 2018,第6期

机译：对比较高性能液相色谱和高性能薄层色谱研究，用于同时测定散装和药物制剂中盐酸二巴基唑辛和二甲双胍
3. Development, Optimization and Validation of New Liquid Chromatographic Method for the Simultaneous Determination H1 Receptor Blockers in Bulk and their Pharmaceutical Formulations by Applying D-Optimal Mixture Design Methodology [J] . Selvakumar Kanthiaha, Valliappan Kannappana Der Pharmacia Lettre . 2016,第21期

机译：D-最佳混合物设计方法同时测定大体积H1受体阻滞剂及其药物配方的新液相色谱方法的开发，优化和验证
4. Optimization of chromatographic conditions for determination of aflatoxin B1, B2, G1 and G2 by using liquid chromatography-mass Spectrometry [C] . Dillani Putri Ramadhaningtyas, Nurhani Aryana, Yosi Aristiawan, International Symposium on Applied Chemistry . 2017

机译：用液相色谱 - 质谱法测定黄曲霉毒素B1，B2，G1和G2的色谱条件的优化
5. High performance liquid chromatographic separation of some psychotherapeutic benzodiazepines with chemometrical optimization. [D] . El-Mubarak, Aarif Hassan. 1995

机译：高效液相色谱分离某些心理治疗性苯二氮卓类药物并进行化学计量优化。
6. A Novel High Performance Liquid Chromatographic Method for Determination of Nystatin in Pharmaceutical Formulations by Box–Behnken Statistical Experiment Design [O] . Farnaz Shokraneh, Ramin Asgharian, Assem Abdollahpour, 2015

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7. Box-Behnken Design Approach for Optimization of a Liquid Chromatographic Method for the Determination of Anti Leukemic Drugs in Bulk and Pharmaceutical Formulations [O] . R. Suresh, M. Swamivelmanickam, S. Sivakrishnan 2020

机译：盒式型液相色谱法测定散液和药物制剂中抗白血病药物的优化设计方法

An Experimental Design Approach to Optimization of the Liquid Chromatographic Separation Conditions for the Determination of Metformin and Glibenclamide in Pharmaceutical Formulation

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