A hybrid system with state-based switchings is proposed to describe the fed-batch production of 1,3-propandiol from glycerol in our previous work. However, the on-off switching of alkali is too frequent, which greatly increases the computational cost of the numerical solution to the system so as to locate the state-based switchings in strict time order and implement the correct mode changes. To deal with this problem, we consider the switching of alkali pump as an impulsive event and present a nonlinear impulsive switching system to describe the fed-batch culture. It is proved that the impulsive switching system is non-Zeno. Some basic properties of solutions to the impulsive switching system are also explored. In order to overcome the discontinuities of the system, the Skorohod topology is induced and a specific form ofλis constructed to prove the main theorem. Additionally, a numerical simulation is carried out to show that the proposed system can describe the fed-batch culture properly and the essential difference with the previous work.
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