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Evaluation of Deceased Kidney Donors for Renal Stone Disease: Is Computed Tomography Needed?

机译:死者肾脏捐献者肾脏结石病的评估:是否需要计算机断层扫描?

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Objective: To investigate the clinical consequences of neglected risk of urolithiasis in deceased kidney donors in routine clinical practice, this study focused on different management options for transplanted allograft stones, and tried to find new solutions for more accurate detection of urolithiasis in deceased kidney donors prior to renal transplantation. Methods and Results: The overall prevalence of stone disease in endemic countries is between 7 and 29%. Because of the increased risk for stone disease in epidemic countries, screening renal grafts from deceased donors necessitates more sensitive imaging tests. Despite well established procedures on preoperative living related renal donor evaluation, there is no consensus on a preoperative imaging tool in cadaveric renal donor evaluation. The most commonly used imaging modality in deceased renal donors is ultrasonography. The overall sensitivity and specificity of ultrasonography for kidney stones are 45 and 88%, respectively. Use of a computed tomography scan for renal diseases, especially for urinary stones is now almost a routine test in clinical practice. Its sensitivity for renal stones 3 mm it is 100%. Conclusion: The use of radiological modalities i.e. computed tomography with higher sensitivity in deceased donors prior to renal transplantation seems reasonable in urinary stone epidemic countries.
机译:目的:在常规临床实践中,研究被遗弃的肾脏捐献者尿路结石风险被忽视的临床后果,本研究关注同种异体移植结石的不同管理选择,并尝试寻找新的解决方案,以更准确地检测已故肾脏捐献者的尿路结石进行肾移植。方法和结果:在流行国家,结石疾病的总患病率为7%至29%。由于在流行国家中患石头病的风险增加,因此从死者的捐献者中筛查肾移植物必须进行更敏感的影像学检查。尽管在术前与生活有关的肾脏供体评估中已经建立了完善的程序,但在尸体肾供体评估中对术前成像工具尚无共识。死者肾脏供体中最常用的成像方式是超声检查。超声检查对肾结石的总体敏感性和特异性分别为45%和88%。对于肾脏疾病,特别是对于尿结石,使用计算机断层扫描已成为临床实践中的常规检查。它对3毫米肾结石的敏感性为100%。结论:在泌尿系结石流行国家中,在肾脏移植前已故的供者中使用放射学方法(即计算机断层扫描)具有更高的敏感性似乎是合理的。

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