Simultaneous Presentation of Waldenstr?m's Macroglobulinemia and MYD88 Gene Mutation with Multiple Myeloma

摘要

Waldenstr?m's macroglobulinemia (WM) and multiple myeloma (MM) are two distinct forms of mature hematologic B-cell malignancies. A?missense somatic mutation in MYD88 gene (MYD88L265P) has been found in hematologic B-cell malignancies. The simultaneous presentation of Waldenstr?m's macroglobulinemia and MYD88 mutation with?multiple myeloma?in the same patient is very rare and only a?few cases have been reported in the literature.