MEG/EEG Source Reconstruction, Statistical Evaluation, and Visualization with NUTMEG

摘要

NUTMEG is a source analysis toolbox geared towards cognitiveneuroscience researchers using MEG and EEG, including intracranialrecordings. Evoked and unaveraged data can be imported to thetoolbox for source analysis in either the time or time-frequencydomains. NUTMEG offers several variants of adaptive beamformers,probabilistic reconstruction algorithms, as well as minimum-normtechniques to generate functional maps of spatiotemporal neuralsource activity. Lead fields can be calculated from single andoverlapping sphere head models or imported from other software. Group averages and statistics can be calculated as well. Inaddition to data analysis tools, NUTMEG provides a unique andintuitive graphical interface for visualization of results. Sourceanalyses can be superimposed onto a structural MRI or headshape toprovide a convenient visual correspondence to anatomy. Theseresults can also be navigated interactively, with the spatial mapsand source time series or spectrogram linked accordingly. Animations can be generated to view the evolution of neuralactivity over time. NUTMEG can also display brain renderings andperform spatial normalization of functional maps using SPM'sengine. As a MATLAB package, the end user may easily link withother toolboxes or add customized functions.