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New Biomarkers in Autoimmune Disease

机译:自身免疫性疾病的新生物标志物

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摘要

Autoimmune diseases are a group of diverse diseases with a common etiology in which the immune system responds to self-antigens leading to damage or dysfunction of tissues. Biomarkers are those measurable substances in the body which associate with the intensity of a disease or other physiological states. Biomarkers can be used in many fields of clinical practice such as disease diagnosis, disease activity evaluation, and disease pathogenesis study. Biomarker research is a rapidly advancing area in autoimmune disease. A variety of researches on discovering new biomarkers including autoantibodies in autoimmune diseases have been conducted in recent years.Based on this background, this special issue presents recent advances for new biomarkers in autoimmune diseases. From 17 submissions, 8 papers are published covering these autoimmune diseases including systemic lupus erythematosus (SLE), lupus nephritis (LN), polymyositis, and ankylosing spondylitis (AS).
机译:自身免疫性疾病是一组具有共同病因的多种疾病,其中免疫系统对自身抗原作出反应,从而导致组织受损或功能障碍。生物标志物是体内与疾病强度或其他生理状态有关的可测量物质。生物标记物可用于临床实践的许多领域,例如疾病诊断,疾病活动性评估和疾病发病机理研究。生物标志物的研究是自身免疫疾病的快速发展领域。近年来,针对发现自身免疫疾病中自身抗体的新生物标志物进行了各种研究,在此背景下,本期专刊介绍了自身免疫疾病中新生物标志物的最新进展。从17篇论文中,发表了8篇论文,涉及这些自身免疫性疾病,包括系统性红斑狼疮(SLE),狼疮性肾炎(LN),多发性肌炎和强直性脊柱炎(AS)。

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