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首页> 外文期刊>Comparative Medicine >Asthma in an Adult Female Vervet Monkey (Chlorocebus sabaeus)
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Asthma in an Adult Female Vervet Monkey (Chlorocebus sabaeus)

机译:成年雌性黑长尾猴(Chlorocebus sabaeus)的哮喘

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摘要

A9-y-old,colony-bred,femalevervetmonkey(Chlorocebussabaeus)presentedwitha6-yhistoryofopen-mouthbreathing,tachypnea,andsibilantwheezing.Thesesymptomsdidnotsignificantlyaffectheractivityorqualityoflife.Thoracicradiographsandresultsofbronchoalveolarlavagesupportedthediagnosisofasthma.Treatmentcomprisingintramuscularprednisolone(taperedover2mofromtwicedailytoeveryotherday),inhaledsalmeterol#8211;fluticasone(25#956;g#8211;250#956;gperactuationtwicedaily)bymask,andametereddoseinhalerwassuccessfulinrestoringanormalrespiratorypattern.Despitetheavailabilityofseveralprimatemodelsofhumanasthma,thiscaserepresentsthefirstreportofspontaneousasthmainaNHP.
机译:A9-Y-老,菌落繁殖,femalevervetmonkey(Chlorocebussabaeus)presentedwitha6-yhistoryofopen-mouthbreathing,呼吸急促,andsibilantwheezing.Thesesymptomsdidnotsignificantlyaffectheractivityorqualityoflife.Thoracicradiographsandresultsofbronchoalveolarlavagesupportedthediagnosisofasthma.Treatmentcomprisingintramuscularprednisolone(taperedover2mofromtwicedailytoeveryotherday),inhaledsalmeterol#8211;氟替卡松(25#956; G#8211; 250#956 ;每天两次操作),尽管有多种灵长类动物模型可利用,但经过调整的剂量吸入器可以成功恢复正常的呼吸模式,这种情况代表了首次报告自发性NHP。

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