Maturity-onset Diabetes of the Young (MODY) Genes: Literature Review

摘要

The aim of this article is to give brief introduction about MODY, its different types and to provide a review of the Genetic Screening and Linkage analysis techniques by analyzing the key properties and advance studies presented throughout the particular bibliography, how different MODY genes have been discovered in different populations. The full text articles related to almost all the MODY genes are downloaded. These papers are critically reviewed. The impact of diverse methodology, advantages and limitations of each of the techniques are described. This paper helps us to understand the potency and weak points of different techniques of Linkage analysis and Genetic Screening in argument by highlighting the strengths and weaknesses of these techniques.