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Hodgkin Lymphoma: Differences in Treatment Between Europe and the United States/North America: Evolving Trends in Protocol Therapy

机译:霍奇金淋巴瘤:欧美之间的治疗差异/北美:协议疗法的发展趋势

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摘要

With continued progress and success in clinical care, the management of patients with Hodgkin lymphoma (HL) has undergone continuous revision to improve patient care outcomes and limit acute and late treatment effects on normal tissue imposed by therapy. Hodgkin lymphoma is a disease that affects children, adolescents, and adults. Clinical management strategies are influenced by the patient’s age at diagnosis, tumor burden, response to induction therapy, and potential expectation of treatment impact on normal tissue. The approach to patient management varies in many parts of the world and is influenced by treatment availability, physician training, and medical culture. Differences in approach are important to understand for accurately comparing and contrasting outcome studies. In this article, we will identify current areas of common ground and points of separation in patient care management for HL. Opportunities for clinical trial strategies will be defined for future clinical trials.
机译:随着临床护理的不断进步和成功,对霍奇金淋巴瘤(HL)患者的治疗已经历了不断的修订,以改善患者的护理效果并限制治疗对正常组织的急性和晚期治疗效果。霍奇金淋巴瘤是一种影响儿童,青少年和成人的疾病。临床管理策略受患者年龄,诊断年龄,肿瘤负担,对诱导疗法的反应以及对正常组织的治疗预期的影响。在世界许多地方,患者管理的方法各不相同,并受治疗方法,医师培训和医疗文化的影响。要准确比较和对比结果研究,方法上的差异很重要。在本文中,我们将确定HL患者护理管理中当前的共同点和分离点。将为将来的临床试验定义临床试验策略的机会。

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