Nutritional assessment, handgrip strength and adductor pollicis muscle thickness in patients with chronic viral hepatitis

摘要

Backgrounds & aimsNutritional status of patients with chronic liver disease has been gaining prominence since it is directly associated to morbidity and mortality. However, there is still no consensus on the best method for nutritional assessment given the great variability of body composition and the several stages of the disease. The objective was to compare different methods of nutritional evaluation of subjects with chronic viral hepatitis (CVH), including handgrip strength (HGS) and adductor pollicis muscle thickness (APMT), as well as their influence factors.MethodsThis cross-sectional study enrolled sixty-nine non-cirrhotic patients with CVH by B or C viruses. Subjects were evaluated and classified through subjective global assessment (SGA), anthropometry, HGS and APMT. Each parameter was compared between gender by chi-square test, and by T test within the categories of SGA. Finally, simple correlation and multivariate linear regression were performed to obtain the strength of association of the collected variables and HGS.ResultsAccording to the SGA, one-third were considered at nutritional risk (SGA-B). Nutritional risk was found in 59.4%, 65.2% and 88% based on HGS, mid-arm muscle circumference (MAMC) and APMT, respectively. The dominant APMT obtained a mean of 17.2?±?5.4?mm vs 16.2?±?4.6?mm of the non-dominant hand. On the other hand, the dominant HGS had a mean of 27.3?±?11.2 vs 24.2?±?11.0 of the non-dominant HGS. APMT and HGS values for any limb were significantly higher in males, but below thresholds patterns described for any gender. The HGS of both hands were correlated with sex, age, weight, height, MAMC, tricipital skinfold and APMT (p?