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Radical Surgery for Endometriosis: Analysis of Quality of Life and Surgical Procedure

机译:子宫内膜异位症的根治手术:生活质量和手术程序分析

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Objective The main aim of this study is to determine the improvement in quality of life in patients who have undergone radical surgery because of severe endometriosis.Patients and Methods This nonrandomized interventional study (quasi experimental) was carried out between January 2009 and September 2014. A total of 46 patients with diagnosis of severe endometriosis were included. Radical surgery, including hysterectomy, was performed. Acting as their own control group, the patients were asked to fill in a validated questionnaire of quality of life [Endometriosis Health Profile-5 (EHP-5)] and a visual analog scale of pain at the moment of the preoperative visit (one month prior to surgery) and six months after the surgery.Results Radical surgery for endometriosis was performed in 46 patients at our center over the period of six years. Among the patients, 73.9% of them had undergone previous surgery for endometriosis. In 82.6% of cases, a complete laparoscopic resection was carried out. Gastrointestinal tract resection was performed in 21.7%, and urinary tract resection was necessary in 8.7%. The mean age of the patients was 38.6 years. The rate of complications was 30.4%. Six months after the surgery, all items of the EHP-5 questionnaire had a lower score, which means an improvement in all aspects of quality of life related to endometriosis. The difference obtained between the scores before and after the surgery was statistically significant. The mean visual analog scale score before the surgery was 8.5, whereas it decreased to 1.4 after the surgery (P < 0.001).Conclusion Performing a radical surgery is a difficult decision to make; however, it can provide optimal results in terms of improvement of quality of life and, therefore, should be considered when conservative therapy fails.
机译:目的本研究的主要目的是确定因严重子宫内膜异位症而接受根治性手术的患者的生活质量改善。患者和方法这项非随机干预研究(准实验性)于2009年1月至2014年9月进行。纳入诊断为严重子宫内膜异位症的46例患者。进行了包括子宫切除在内的根治性手术。作为他们自己的对照组,患者被要求填写一份经验证的生活质量调查表[子宫内膜异位症健康状况-5(EHP-5)]和术前就诊时(一个月)的视觉模拟疼痛量表结果六年内,我们中心对46例患者进行了根治性子宫内膜异位症的根治性手术。在这些患者中,有73.9%曾接受过子宫内膜异位手术。在82.6%的病例中,进行了完全腹腔镜切除。胃肠道切除术占21.7%,泌尿系切除术占8.7%。患者的平均年龄为38.6岁。并发症发生率为30.4%。手术六个月后,EHP-5问卷的所有项目得分均较低,这意味着与子宫内膜异位症相关的生活质量的所有方面均得到改善。手术前后得分之间的差异具有统计学意义。手术前平均视觉模拟量表评分为8.5,而手术后平均评分降至1.4(P <0.001)。结论进行根治性手术是一项艰难的决定;但是,它可以提供改善生活质量的最佳结果,因此,当保守治疗失败时应考虑使用。

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