O6-Methylguanine DNA Methyltransferase Gene Promoter Methylation Status in Gliomas and Its Correlation With Other Molecular Alterations: First Indian Report With Review of Challenges for Use in Customized Treatment

Jha Prerana; Suri Vaishali; Jain Ayushi; Sharma Mehar Chand; Pathak Pankaj; Jha Pankaj; Srivastava Arti; Suri Ashish; Gupta Deepak; Chosdol Kunzang; Chattopadhyay Parthoprasad; Sarkar Chitra

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O6-Methylguanine DNA Methyltransferase Gene Promoter Methylation Status in Gliomas and Its Correlation With Other Molecular Alterations: First Indian Report With Review of Challenges for Use in Customized Treatment

机译：胶质瘤中的O6-甲基鸟嘌呤DNA甲基转移酶基因启动子甲基化状态及其与其他分子变化的关系：首次印度报告，对定制治疗的挑战进行了综述

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AbstractBACKGROUND:. O6-methylguanine methyltransferase (MGMT) promoter methylation in adult glioblastomas (glioblastoma multiforme) is considered a promising.

机译：摘要背景：成人胶质母细胞瘤（多形胶质母细胞瘤）中的O6-甲基鸟嘌呤甲基转移酶（MGMT）启动子甲基化被认为是有希望的。

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《Clinical neurosurgery.》 |2010年第6期|共11页
作者
Jha Prerana; Suri Vaishali; Jain Ayushi; Sharma Mehar Chand; Pathak Pankaj; Jha Pankaj; Srivastava Arti; Suri Ashish; Gupta Deepak; Chosdol Kunzang; Chattopadhyay Parthoprasad; Sarkar Chitra;
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中图分类头部及神经外科学;
关键词
gliomamethylationepidermal growth factor receptorstp53 geneneoplasmsloss of heterozygosity;

机译：胶质瘤甲基化表皮生长因子受体stp53基因质杂合性缺失;

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1. O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment. [J] . Suri V, Jain A, Sharma MC, Neurosurgery . 2010,第6期

机译：胶质瘤中的O6-甲基鸟嘌呤DNA甲基转移酶基因启动子甲基化状态及其与其他分子改变的相关性：印度首次发表关于定制治疗中使用的挑战的报告。
2. Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study. [J] . Brandes AA, Tosoni A, Cavallo G, Journal of Clinical Oncology . 2006,第29期

机译：间变性和复发性少突胶质细胞瘤中O6-甲基鸟嘌呤DNA甲基转移酶启动子甲基化状态，1p和19q缺失与替莫唑胺反应的相关性：前瞻性GICNO研究。
3. O6-methylguanine DNA methyltransferase gene promoter methylation status in glioblastoma and its correlation with other prognostic markers [J] . Chang Suk Kang, Suk Woo Nam, Sung Hak Lee, Molecular & Cellular Toxicology . 2012,第4期

机译：胶质母细胞瘤中O6-甲基鸟嘌呤DNA甲基转移酶基因启动子甲基化状态及其与其他预后指标的相关性
4. P14.36 Treatment patterns by O6-methylguanine DNA methyltransferase promoter (MGMT) status in newly-diagnosed glioblastoma multiforme (GBM): a multi-country chart review study [O] . A Z Fu, G J Thompson, J P Hall, 2019

机译：P14.36通过O6-甲基胍DNA甲基转移酶启动子（MGMT）的治疗模式在新诊断的胶质母细胞瘤多形状（GBM）：一个多国图表审查研究
5. MRI-BASED DEEP LEARNING METHOD FOR DETERMINING METHYLATION STATUS OF THE O6-METHYLGUANINE–DNA METHYLTRANSFERASE PROMOTER OUTPERFORMS TISSUE BASED METHODS IN BRAIN GLIOMAS [O] . Chandan Ganesh Bangalore Yogananda, Bhavya R. Shah, Sahil S. Nalawade, 2020

机译：基于MRI的深度学习方法，用于测定O6-甲基胍-DNA-DNA甲基转移酶启动子的甲基化状态优于脑胶质瘤中基于组织的方法

O6-Methylguanine DNA Methyltransferase Gene Promoter Methylation Status in Gliomas and Its Correlation With Other Molecular Alterations: First Indian Report With Review of Challenges for Use in Customized Treatment

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