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Unexpected Abscess Localization of the Anterior Abdominal Wall in an ADPKD Patient Undergoing Hemodialysis

机译:接受血液透析的ADPKD患者的前腹壁意外脓肿定位

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Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the most common monogenic disorders and the leading inheritable cause of end-stage renal disease worldwide. Cystic and noncystic extrarenal manifestations are correlated with variable clinical presentations so that an inherited disorder is now considered a systemic disease. Kidney and liver cystic infections are the most common infectious complications in ADPKD patients. Furthermore, it is well known that ADPKD is commonly associated with colonic diverticular disease which recently has been reported to be linked to increased risk of infection on hemodialysis patients. Herein, we present a case of anterior abdominal wall abscess caused byEnterococcus faecalisin a patient with ADPKD undergoing hemodialysis. Although the precise pathway of infection remains uncertain, the previous medical history as well as the clinical course of our patient led us to hypothesize an alternative route of infection from the gastrointestinal tract through an aberrant intestinal barrier into the bloodstream and eventually to an atypical location.
机译:常染色体显性多囊肾病(ADPKD)是全球最常见的单基因疾病之一,也是终末期肾脏疾病的主要遗传病因。囊性和非囊性肾外表现与多种临床表现相关,因此,遗传性疾病现在被认为是全身性疾病。肾脏和肝囊性感染是ADPKD患者最常见的感染并发症。此外,众所周知,ADPKD通常与结肠憩室病有关,最近已报道它与血液透析患者感染的风险增加有关。本文中,我们介绍了由粪肠球菌引起的ADPKD血液透析患者引起的前腹壁脓肿的病例。尽管确切的感染途径仍不确定,但是根据患者的既往病史和临床病历,我们推测出了从胃肠道通过异常肠屏障进入血流并最终到达非典型位置的另一种感染途径。

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