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首页> 外文期刊>Bangladesh Journal of Medical Science >A review of adult head and neck soft tissue sarcoma in a tertiary centre: malaysia experience
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A review of adult head and neck soft tissue sarcoma in a tertiary centre: malaysia experience

机译:第三中心成人头颈部软组织肉瘤的回顾:马来西亚经验

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Background: Head and neck tissue sarcoma are rare with potential high morbidity and mortality. The purpose of the present study was to present these cases and determine the optimal treatment for adult patients with head and neck soft tissue sarcomas.Methods: It is a retrospective study of adult head and neck soft tissue sarcoma conducted in the Department of Otorhinolaryngology at Universiti Kebangsaan Malaysia Medical Centre (UKMMC) which is one of the national referral center within the period of 16 years from 1998 till 2014.Results: Fourteen cases were reviewed in which7 histopathological variations of soft tissue sarcomas were identified. Local control after surgery alone or combined with radiotherapy was obtained in 50 % of the patients which is influenced by histologic grade, tumor size, and surgical margins. Patients with high-grade tumors or positive margins have improved local control if adjuvant radiotherapy is used. Distant metastases occurred in 14.2 % of patients and the 5-year survival rate was 50 %.Conclusions: The optimal treatment for adult head and neck soft tissue sarcomas is surgery. Adjuvant radiotherapy improves outcomes for those with high-grade tumors or positive margins.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.69-76
机译:背景:头颈部组织肉瘤很少见,具有较高的发病率和死亡率。本研究的目的是介绍这些病例并确定成人头颈部软组织肉瘤的最佳治疗方法。方法:这是在大学耳鼻喉科进行的成人头颈部软组织肉瘤的回顾性研究。 1998年至2014年的16年内,马来西亚国家级转诊中心之一的Kebangsaan马来西亚医学中心(UKMMC)。结果:回顾了14例病例,发现了7例软组织肉瘤的组织病理学变化。 50%的患者接受了单独手术或联合放疗后的局部控制,这受组织学等级,肿瘤大小和手术切缘的影响。如果使用辅助放疗,则患有高级别肿瘤或切缘阳性的患者可改善局部控制。 14.2%的患者发生远处转移,五年生存率为50%。结论:成人头颈部软组织肉瘤的最佳治疗方法是手术。辅助放疗可改善高级别肿瘤或切缘阳性的患者的疗效。孟加拉国医学杂志Vol.16(1)2017 p.69-76

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