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Bacillary Angiomatosis and Bacteremia due toBartonella quintanain a Patient with Chronic Lymphocytic Leukemia

机译:巴尔通体金刚菌素引起的细菌性血管瘤病和细菌血症的慢性淋巴细胞性白血病

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We present a 63-year-old man treated with alemtuzumab for chronic lymphocytic leukemia who developed multiple angiomatous papules and fever. Real-time polymerase chain reaction (RT-PCR) from a skin lesion and blood sample revealedBartonella quintanaas causative agent confirming the diagnosis of bacillary angiomatosis with bacteremia. Treatment with doxycycline, initially in combination with gentamicin, led to complete resolution of the lesions. This case shows the importance of considering bacillary angiomatosis as a rare differential diagnosis of angiomatous lesions in the immunocompromised patient, particularly in chronic lymphocytic leukemia and following lymphocyte depleting treatments as alemtuzumab.
机译:我们介绍了一位63岁的男性,他接受了alemtuzumab治疗的慢性淋巴细胞性白血病,并发展为多发性血管瘤性丘疹和发烧。皮肤病变和血液样本中的实时聚合酶链反应(RT-PCR)显示,金黄色通心粉病的病原体证实了细菌性细菌性血管瘤病的诊断。最初与庆大霉素联用的强力霉素进行治疗可完全治愈病变。该案例表明,考虑将细菌性血管瘤病作为免疫受损患者中血管瘤病变的罕见鉴别诊断的重要性,尤其是在慢性淋巴细胞性白血病以及在淋巴细胞减少治疗后如阿仑单抗中。

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