Exacerbation of Darier Disease under Interferon-???±-2a Therapy with Clinical Signs of Lichen Nitidus

摘要

Darier disease/dyskeratosis follicularis is a genodermatosis characterized by brown, oily keratotic papules and plaques in the seborrheic areas of the face and chest. Responsible for the disease are mutations in the ATP2A2 gene, encoding SERCA2, a calcium