Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

RashmeePatil; Mel A.Ona; HarisPapafragkakis; JeanneCarey; YitzchakMoshenyat; AdibAlhaddad; SuryAnand

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Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

机译：依法韦仑/恩曲他滨/替诺福韦引起的急性肝毒性

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The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated aminotransferase levels, which resolved without acute liver failure or need for liver transplant referral.

机译：依非韦伦/依米卡他滨/替诺福韦的固定剂量组合是治疗HIV的一线药物;然而，很少有病例报道与该药物相关的肝毒性。我们报告一例依法韦仑/依米他滨/替诺福韦相关的肝毒性病例，主要表现为肝细胞损伤，其特征是转氨酶水平极高，可解决而无急性肝衰竭或需要肝移植转诊。

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《Case Reports in Hepatology》 |2015年第1期|共2页
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RashmeePatil; Mel A.Ona; HarisPapafragkakis; JeanneCarey; YitzchakMoshenyat; AdibAlhaddad; SuryAnand;
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中图分类临床医学;
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1. First‐line antiretroviral therapy with efavirenz plus tenofovir disiproxil fumarate/emtricitabine or rilpivirine plus tenofovir disiproxil fumarate/emtricitabine: a durability comparison [J] . Taramasso L, Di Biagio A, Maggiolo F, HIV medicine . 2018,第7期

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2. 3-Year efficacy and durability of simplification to single tablet regimens: a comparison between co-formulated efavirenz/emtricitabine/tenofovir and rilpivirine/emtricitabine/tenofovir. [J] . Roberta Gagliardini, Alessandra Bandera, Mauro Zaccarelli, Antiviral therapy . 2018,第2期

机译：单片机方案简化的3年疗效和耐用性：共同配制的Efaviraz / Emtricisabine / Tenofovir和Rilpivirine / Emtricitabine / Tenofovir之间的比较。
3. Viral blips were infrequent in treatment-naive adults treated with rilpivirine/emtricitabine/tenofovir DF or efavirenz emtricitabine/tenofovir DF through 96 weeks [J] . Porter Danielle P., Kulkarni Rima, Garner Will, Antiviral therapy . 2017,第6期

机译：治疗野生成年人患有瑞吉柳柳胺/ Emtricicabine / Tenofovir DF或Efavirenz Emtrickabine / Tenofovir DF至96周的病毒分层罕见
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6. Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir [O] . Rashmee Patil, Mel A. Ona, Haris Papafragkakis, 2015

机译：依法韦仑/恩曲他滨/替诺福韦引起的急性肝毒性
7. First-line antiretroviral therapy with efavirenz plus tenofovir disiproxil fumarate/emtricitabine or rilpivirine plus tenofovir disiproxil fumarate/emtricitabine: a durability comparison [O] . L Taramasso, A Di Biagio, F Maggiolo, 2018

机译：用Efaviraz Plus Tenofovir Disiproverxil富马酸盐/ Emtrickabine或Rilpirovir Plus Tenofovir Disiproxil Fumarate / Emtrickabine：耐久性比较

Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

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