PRIMARY NEUROENDOCRINE CARCINOMA OF THE BREAST; CASE REPORT. Memenin primer n?roendokrin karsinomu; Olgu sunumu.

摘要

Primary neuroendocrine carcinoma of the breast is an extremely rare tumor. Tumours can only be considered small cell neuroendocrine tumour of the breast if nonmammary sites are excluded. We present our experience of primary neuroendocrine carcinoma of the breast in a 76-year-old woman and 87-year-old woman. First patient has presented with just about4 cmpalpable mass in her left breast. Tru cut biopsy from left breast showed a invasive carcinoma. Wide surgical excision and sentinel lymph node biopsy were performed. The second patient admitted our clinic complaints of a mass in her left breast. Because of limitted cardiac failure, only lumpectomy was performed with local anestesia. Also in two patients, immunohistochemical staining showed primary neuroendocrine carcinoma of the breast. Computed tomography scans of the chest and abdomen showed no lesion for metastasis or another primary origin. Adjuvant hormone therapy was given, since the tumor was immunohistochemically receptor positive.??ZETMemenin primer n?roendokrin karsinomu, olduk?a nadir g?rülen bir tüm?rdür. Tüm?rün primer olarak meme kaynakl? oldu?unu s?ylemek i?in meme d??? organlarda olmad??? kan?tlanmal?d?r. Bu ?al??mada, memenin primer n?roendokrin tüm?rü tan?s? koy-du?umuz 76 ve 87 ya??ndaki iki kad?n hastam?za ait tecrübemizi sunduk. ?lk hastam?z sol memede yakla??k 4 cmlik kitle ?ikayeti ile ba?vurdu. Yap?lan tru cut biyopsi sonucu invazif karsinom olarak sonu?land?. Hastaya sentinel lenf nodu biyopsisi ve geni? cerrahi eksizyon uyguland?. ?kinci hastam?z sol memede kitle ile klni?imize ba?vurdu. ?leri kardiyak yetersizli?i olan hastaya lokal anestezi alt?nda yaln?zca lumpektomi uyguland?. Her iki hastada immunhistokimyasal boyamalar sonucunda memenin primer n?roendok-rin karsinomu saptand?. Toraks ve bat?na y?nelik bilgisayarl? tomografi incelemelerinde metastaz saptanmad?. Resept?rleri pozitif olan hastalara sonraki d?nemde hormonoterapi verildi.