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Granulomatosis with Polyangiitis Presenting as a Choroidal Tumor

机译:肉芽肿合并血管炎的多血管炎

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Granulomatosis with polyangiitis (GPA) sometimes involves the eye orbit; however, choroidal involvements in GPA had been rarely reported. We report a rare case presenting with a choroidal mass in an 83-year-old Japanese woman who presented with left eye pain. Diagnostic biopsy revealed necrotizing vasculitis with infiltrates of inflammatory cells. Diagnosis was localized granulomatosis with polyangiitis. Combined treatments with corticosteroid plus azathioprine resolved the choroidal mass region. Although treatment with corticosteroid and immunosuppressive agents improves the prognosis of the disease, ocular morbidity is still well recognized. Clinicians should consider a differential diagnosis of GPA in patients with inflammatory choroidal tumors.
机译:肉芽肿性多血管炎(GPA)有时会累及眼眶。但是,很少有人报道脉络膜受累于GPA。我们报道了一位83岁的日本女性,出现左眼疼痛的罕见病例,显示脉络膜肿块。诊断性活检显示坏死性血管炎伴炎性细胞浸润。诊断为局部肉芽肿伴多血管炎。皮质类固醇加硫唑嘌呤联合治疗可解决脉络膜肿块区域。尽管用皮质类固醇和免疫抑制剂治疗可改善疾病的预后,但眼病的发生率仍得到公认。临床医生应考虑对炎性脉络膜肿瘤患者进行GPA的鉴别诊断。

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