DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

MingJie Ma; Yu Hasegawa; Nobutaka Koibuchi; Kensuke Toyama; Ken Uekawa; Takashi Nakagawa; Bowen Lin; Shokei Kim-Mitsuyama

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DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

机译：利格列汀对DPP-4的抑制可改善2型糖尿病小鼠短暂性脑缺血所致的认知障碍和脑萎缩

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《Cardiovascular Diabetology》 |2015年第1期|共页
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MingJie Ma; Yu Hasegawa; Nobutaka Koibuchi; Kensuke Toyama; Ken Uekawa; Takashi Nakagawa; Bowen Lin; Shokei Kim-Mitsuyama;
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1. Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin- Induced Diabetic Mice by Inhibiting Endothelial-to- Mesenchymal Transition in a Therapeutic Regimen [J] . Keizo Kanasaki, Sen Shi, Megumi Kanasaki, Diabetes . 2014,第6期

机译：利拉列汀介导的DPP-4抑制作用通过抑制治疗方案中的内皮细胞向间充质转化来缓解链脲佐菌素诱导的糖尿病小鼠的肾脏纤维化。
2. Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice [J] . Renana Baratz, David Tweedie, Jia-Yi Wang, Journal of neuroinflammation . 2015,第3期

机译：短暂降低肿瘤坏死因子-α合成可减轻小鼠轻度脑外伤所致的神经元细胞丢失和认知障碍
3. Hyperbaric oxygen alleviated cognitive impairments in mice induced by repeated cerebral ischemia-reperfusion injury via inhibition of autophagy [J] . Chen Chunxia, Chen Wan, Nong Zhihuan, Life sciences . 2020,第1期

机译：通过抑制自噬通过反复脑缺血再灌注损伤诱导的小鼠中的高压氧气减轻了认知障碍
4. Empagliflozin and linagliptin ameliorate podocyte injury and enhance autophagy in a model of type 2 diabetic nephropathy [C] . Anton Korbut, Vadim. Klimontov, Iuliia Taskaeva, . 2018

机译：Empagliflozin和linagliptin改善2型糖尿病肾病模型中的足细胞损伤并增强自噬
5. GLP-1R Agonists Improve Cerebrovascular Integrity and Vascular Cognitive Impairment and Dementia (VCID) beyond Glycemic Control via Recovery of Brain Pericyte Function in Diabetic Mice [D] . Bailey, Joseph. 2020

机译：GLP-1R激动剂通过在糖尿病小鼠中培养脑周细胞功能来改善脑血管完整性和血管认知障碍和痴呆（VCID）超越血糖控制
6. DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice [O] . MingJie Ma, Yu Hasegawa, Nobutaka Koibuchi, 2015

机译：利拉列汀对DPP-4的抑制作用可改善2型糖尿病小鼠短暂性脑缺血所致的认知障碍和脑萎缩
7. DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice [O] . 2015

机译：利拉列汀对DPP-4的抑制作用可改善2型糖尿病小鼠短暂性脑缺血所致的认知障碍和脑萎缩

DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

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