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Pseudoepitheliomatous Hyperplasia of the Larynx Requiring Total Laryngectomy

机译:喉上皮假上皮瘤样增生需要全喉切除术

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Objective: Unusual clinical courseBackground: Pseudoepitheliomatous hyperplasia (PEH) is a reactive epithelial proliferation occurring secondary to infection, neoplasm, injury, and inflammation. The histopathological characteristics of PEH may lead to it being confused with well-differentiated squamous cell carcinoma (SCC).Case Report: We present here the case of a 57-year-old male patient, who was diabetic and a smoker, who presented with dysphonia. Although nasal endoscopy suggested SCC, morphological and immunophenotypical study of biop-sy tissue ruled out malignancy.Conclusions: As the prognosis worsened, the patient required several urgent surgical interventions due to bleeding abscess-es and dyspnea. A total laryngectomy was performed.
机译:目的:异常的临床过程背景:假上皮增生(PEH)是一种反应性上皮增生,继发于感染,肿瘤,损伤和炎症。 PEH的组织病理学特征可能导致其与高度分化的鳞状细胞癌(SCC)混淆。病例报告:我们在这里报道了一名57岁的男性患者,该患者是糖尿病患者和吸烟者,声音障碍。尽管鼻内镜检查提示有鳞状上皮性癌,但活检组织的形态学和免疫表型研究排除了恶性肿瘤。结论:由于预后恶化,该患者由于脓肿和呼吸困难而需要采取一些紧急外科手术。进行了全喉切除术。

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