A case report of acute dystonia caused by a therapeutic dose of metoclopramide

摘要

Metoclopramide is a dopamine receptor antagonist, frequently used as an antiemetic drug. Side effects include extrapyramidal reactions such as tardive dyskinesia, Parkinsonism, akathisia, neuroleptic malignant syndrome, and acute dystonic reaction requiring acute intervention. While the incidence of acute dystonic reaction is 0.5-1% in children, it is 25% in young adults and elderly. Patients can be misdiagnosed with meningitis, encephalitis, hypocalcaemia, seizures, and tetanus. In this report, a 24-year-old woman with acute dystonia precipitated by a therapeutic dose of metoclopramide, is presented.