Selenium protective activity against aflatoxin B1 adverse affects on Drosophila melanogaster

摘要

The aim of this work was to investigate the effects of AFB1 and AFB1+Se4+ on various developmental stages of Drosophila melanogaster were investigated. Both different concentrations of AFB1 and Se4+ applied with AFB1 were fed during the flies developmental period (egg, larva and pupae). When F1 progeny of control and application groups were compared with each other, AFB1 was found to have extending the process of metamorphosis and decreasing the total number of offsprings. But, these negative effects were inhibited with selenium treatment at different concentrations (4.0 and 8.0 ppm). These results suggested that selenium could effectively inhibit AFB1- induced abnormalities of the developmental stages of D.melanogaster.