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Current management of oesophageal cancer

机译:食管癌的当前管理

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Background: Oesophageal cancer is the eighth most common cancer and it’s the sixth leading cause of death in the world. The five years overall survival is reported to be between 15-20%. The aim of this review is to highlight the current trends of management of oesophageal cancer. Methods: A literature search of PubMed/MEDLINE, EMBASE and Cochrane Library and Central Register of Controlled Trials (CENTRAL) databases up to November 2014 was conducted. Results: Oesophageal cancer accounts for almost 3% of all cancers and is the ninth most common malignancy in the UK. Diagnosis is usually made by oesophago-gastro-duodenoscopy where multiple biopsy samples must be taken from any mucosal abnormality to exclude early tumours. The management of oesophageal cancers requires a multi-disciplinary team approach involving surgeons, oncologists, radiologists, pathologists, specialist nurses, dietitians and specialists from other specialties if required. Conclusions: Treatment of oesophageal cancer is still a challenge however recent advances in surgery, endoscopic treatments and new therapeutic agents will hopefully improve prognosis.
机译:背景:食道癌是世界上第八大常见癌症,也是全球第六大死亡原因。据报道五年的总生存率在15%至20%之间。这篇综述的目的是强调食管癌治疗的当前趋势。方法:对截至2014年11月的PubMed / MEDLINE,EMBASE和Cochrane图书馆以及对照试验中央注册数据库(CENTRAL)进行了文献检索。结果:食道癌几乎占所有癌症的3%,是英国第九大最常见的恶性肿瘤。诊断通常通过食管-胃-十二指肠镜进行,其中必须从任何粘膜异常中取多个活检样本以排除早期肿瘤。食道癌的管理需要跨学科的团队方法,包括外科医生,肿瘤学家,放射学家,病理学家,专科护士,营养师和其他专业的专家(如果需要)。结论:食管癌的治疗仍然是一个挑战,但是手术,内窥镜治疗和新治疗药物的最新进展有望改善预后。

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