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Risk behavior in patients with severe mental disorders: a prospective study of 121,830 patients managed in rural households of western China

机译:严重精神障碍患者的风险行为:对中国西部农村家庭管理的121,830名患者的前瞻性研究

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The management of severe mental disorder (SMD) patients in communities is an important initiative of healthcare reform in China. Yet the effects in terms of risk behavior of patients are unclear, particularly in rural areas. This study aims to examine high risk behaviors, changing trends, and possible associated factors among SMD patients in the rural areas of western China. This analysis examined incidence rate (IR) of high risk behavior of 121,830 managed SMD patients in rural area of Sichuan province, based on data from the national system from 2006 to 2013. Register rate, high risk behavior IR, and time distribution and area distribution of high risk behavior were described. Two-level Poisson regression model was used to analyze associates of high risk behavior of patients, which include demographic characteristics at individual level, socio-economic condition and health system indicators at region level. It was revealed that 6804 (5.58%) of managed patients were involved in 17,220 high risk behavior events, which gave an overall IR of 0.0998 (per person year) on the basis of 172,564 person years of follow-up. The IR varied widely across municipalities, in the range of 0.0305–0.3397. The IR of high risk behavior in the cohort had increased since 2006, and peaked by 2011, at 0.2392. At the individual level, males aged 25 to 44, who were unmarried and in poverty, illiterate or semiliterate, had a family history of mental disorders and antipsychotic treatments, longer duration illnesses, were associated with an increased IR risk. At the regional level, higher psychiatric practitioner visits and the lower annual net income of rural residents per capita, were associated with an increased IR risk. This is the first large prospective study that revealed the current situation of the register rate, high risk behavior incidence rate in SMD patients in rural area of western China, and examined associates and the differences of high risk behavior of patients among municipalities. The findings may provide evidences that lead to guide prevention and control for risk behavior in SMD patients in rural areas of China, as well as to improve mental health services for this population. It could provide some reference for other developing countries too.
机译:社区严重精神障碍患者的管理是中国医疗改革的重要举措。然而,关于患者危险行为的影响尚不清楚,尤其是在农村地区。本研究旨在检查中国西部农村地区SMD患者的高危行为,变化趋势以及可能的相关因素。该分析基于2006年至2013年国家系统的数据,检查了四川省农村地区121,830名管理SMD患者的高危行为发生率(IR)。登记率,高危行为IR以及时间分布和区域分布描述了高风险行为。使用两级Poisson回归模型分析患者的高风险行为,包括个人水平的人口统计学特征,社会经济状况和地区水平的卫生系统指标。结果表明,接受管理的患者中有6804名患者(5.58%)参与了17220次高危行为事件,在172564人年的随访基础上,总IR为0.0998(每人年)。各个城市的IR差异很大,范围在0.0305-0.3397之间。自2006年以来,该队列中高风险行为的IR有所增加,到2011年达到峰值,为0.2392。在个人层面上,未婚且处于贫困,文盲或半文盲的25岁至44岁男性,有家族精神病史和抗精神病药物治疗,病程较长,与IR风险增加相关。在区域一级,精神科医师就诊次数增加,农村居民人均年纯收入降低,与IR风险增加有关。这是第一项大型前瞻性研究,揭示了中国西部农村地区SMD患者的登记率,高危行为发生率的现状,并研究了城市居民之间同伴和患者高危行为的差异。该发现可能提供证据,以指导中国农村SMD患者的危险行为的预防和控制,以及改善该人群的心理健康服务。它也可以为其他发展中国家提供参考。

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