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Treatment of lead and arsenic poisoning in anuric patients – a case report and narrative review of the literature

机译:无尿患者铅和砷中毒的治疗-病例报告和文献综述

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摘要

Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered. We present a case of symptomatic lead and arsenic poisoning from use of Ayurvedic medicine in a 28-year-old man with end-stage kidney disease on chronic hemodialysis. We describe his treatment course with chelating agents and extracorporeal blood purification, and review the relevant literature to provide general guidance. Cumulative clinical experience assists in identifying preferred chelators and modalities of extracorporeal blood purification when managing such patients. However, a larger body of real-world or clinical trial evidence is necessary to inform evidence-based guidelines for the management of heavy metal poisoning in anuric patients.
机译:如果不及时治疗,重金属中毒会导致使人衰弱的疾病,而无尿患者的重金属中毒则面临挑战。指导该领域临床实践的文献相当分散。我们在一个患有慢性肾脏透析终末期肾脏疾病的28岁男性中,使用阿育吠陀药物治疗,导致一例症状性铅和砷中毒。我们用螯合剂和体外血液净化来描述他的治疗过程,并复习相关文献以提供一般指导。累积的临床经验有助于在管理此类患者时确定首选的螯合剂和体外血液净化的方式。但是,有必要提供大量的现实世界或临床试验证据来指导基于证据的指导,用于治疗无尿患者的重金属中毒。

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