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首页> 外文期刊>Brazilian journal of chemical engineering >Study of the microwave vacuum drying process for a granulated product
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Study of the microwave vacuum drying process for a granulated product

机译:颗粒产品的微波真空干燥工艺研究

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The objectives of this work were to study and evaluate the process of drying a pharmaceutical granule from 21% to 3 % (d.b.) moisture, also determining the power absorbed by the product, using a microwave assisted vacuum dryer with two absolute pressures: 50 and 75 mbar. A specific objective was to compare the drying kinetics of the microwave assisted vacuum process (MAVP) with two other drying processes, one using hot air convection and the other combining microwaves with hot air convection. The results of such a study showed that the drying kinetics were not affected by the vacuum levels, whereas the absorbed microwave power was higher for smaller vacuum levels. It was also observed that the samples obtained by the microwave assisted vacuum process, when submitted to compression, complied with the required specifications. The drying kinetics of the MAVP showed the shortest drying times when compared to the other drying processes.
机译:这项工作的目的是研究和评估将药物颗粒从21%的水分干燥到3%(db)的水分的过程,并使用微波辅助真空干燥机在两个绝对压力下分别确定产品吸收的功率:50和75毫巴一个特定的目标是将微波辅助真空工艺(MAVP)的干燥动力学与其他两种干燥工艺进行比较,一种使用热空气对流,另一种将微波与热空气对流结合。这项研究的结果表明,干燥动力学不受真空度的影响,而对于较小的真空度,吸收的微波功率较高。还观察到,通过微波辅助真空工艺获得的样品在进行压缩时符合要求的规格。与其他干燥工艺相比,MAVP的干燥动力学显示出最短的干燥时间。

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