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Challenges affecting prompt access to adequate uncomplicated malaria case management in children in rural primary health facilities in Chikhwawa Malawi

机译:挑战影响到奇瓦瓦马拉维农村初级卫生保健机构中的儿童迅速获得充分,简单的疟疾病例管理

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Reducing the burden of malaria highly depends on access to prompt and effective malaria diagnosis and treatment. The aim of this study was to identify challenges affecting prompt access to effective uncomplicated malaria case management in children below 10?years old in rural primary health care facilities in Malawi. A cross sectional health facility survey was conducted in six primary health facilities in Chikhwawa district, Malawi. Officers-in-charge of health facilities were interviewed on availability of staff, supplies and drugs. All consecutive children presenting at the facility with fever or suspected malaria, aged 6?months to 10?years old, were eligible to participate in exit interviews. Exit interviews with participants’ guardians assessed duration of illness, demographic information and distance travelled. Adherence to recommended malaria case management guidelines included performing malaria rapid diagnostic tests (mRDTs) in children with fever or suspected malaria and prescribing recommended weight-based dose of artemether-lumefantrine (AL) when mRDT was positive. Multivariate logistic regression was used to determine factors associated with prompt care seeking within 24?h of onset of illness. Health facilities were staffed by at least two health workers. Of 265 children screened, nine were excluded due to severe illness. Twenty-one percent of children presenting at a health facility with fever were not tested for malaria. Adherence to positive and negative mRDT results for those tested was 99.4, 95% CI [98.1–100] and 97, 95% CI [88.9–100], respectively. AL was prescribed as recommended by weight in 152 children (92.2%). Temporary stock outs of AL occurred in five of six facilities. In total, 146 (57, 95% CI [52.7–64.1]) guardians of patients sought care within 24?h after fever onset. Children aged 5 to 10?years were less likely to present within 24?h of fever onset than children below 5?years of age (unadjusted odds ratio 0.40, 95% CI [0.2–0.7]). Adherence to malaria diagnosis and treatment guidelines was high. However, delayed care seeking and stock outs may affect prompt and effective malaria case management. Further qualitative work is required to determine, and address factors associated with delay in care seeking for fever.
机译:减轻疟疾负担在很大程度上取决于能否获得迅速有效的疟疾诊断和治疗。这项研究的目的是找出影响马拉维农村初级卫生保健机构中10岁以下儿童迅速获得有效的简单疟疾病例管理的挑战。在马拉维奇克瓦瓦地区的六个主要卫生设施中进行了横断面卫生设施调查。对卫生设施负责人进行了工作人员,用品和药品供应情况的采访。在该机构就诊的所有连续发烧或疑似疟疾的儿童,年龄在6个月至10岁之间,均符合参加出口访谈的条件。参加者监护人的出口访谈评估了疾病的持续时间,人口统计信息和旅行距离。遵守推荐的疟疾病例管理指南包括对发烧或疑似疟疾的儿童进行疟疾快速诊断测试(mRDT),并在mRDT呈阳性时开出建议的基于剂量的蒿甲醚-卢美他汀(AL)推荐剂量。多元logistic回归用于确定与发病后24小时内寻求即时护理有关的因素。卫生设施至少有两名卫生工作者。在筛选的265名儿童中,有9名因重病被排除在外。在医疗机构中出现发烧的儿童中,有21%没有进行疟疾检测。受测者对mRDT阳性和阴性结果的依从性分别为99.4、95%CI [98.1-100]和97、95%CI [88.9-100]。 152名儿童(92.2%)按体重推荐服用AL。 AL的临时缺货发生在六个工厂中的五个中。总共146名患者(57,95%CI [52.7-64.1])的监护人在发烧后24小时内寻求护理。 5至10岁的儿童比5岁以下的儿童在发烧24小时内出现的可能性较小(未调整优势比0.40,95%CI [0.2-0.7])。对疟疾诊断和治疗指南的遵守率很高。但是,延迟的求医和缺货可能会影响及时有效的疟疾病例管理。需要进一步的定性工作来确定和解决与发烧延误护理有关的因素。

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