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Patient-, health worker-, and health facility-level determinants of correct malaria case management at publicly funded health facilities in Malawi: results from a nationally representative health facility survey

机译:马拉维公共资助的医疗机构中正确的疟疾病例管理的患者,医务人员和医疗机构级别的决定因素:一项全国代表性的医疗机构调查的结果

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Background Prompt and effective case management is needed to reduce malaria morbidity and mortality. However, malaria diagnosis and treatment is a multistep process that remains problematic in many settings, resulting in missed opportunities for effective treatment as well as overtreatment of patients without malaria. Methods Prior to the widespread roll-out of malaria rapid diagnostic tests (RDTs) in late 2011, a national, cross-sectional, complex-sample, health facility survey was conducted in Malawi to assess patient-, health worker-, and health facility-level factors associated with malaria case management quality using multivariate Poisson regression models. Results Among the 2,019 patients surveyed, 34% had confirmed malaria defined as presence of fever and parasitaemia on a reference blood smear. Sixty-seven per cent of patients with confirmed malaria were correctly prescribed the first-line anti-malarial, with most cases of incorrect treatment due to missed diagnosis; 31% of patients without confirmed malaria were overtreated with an anti-malarial. More than one-quarter of patients were not assessed for fever or history of fever by health workers. The most important determinants of correct malaria case management were patient-level clinical symptoms, such as spontaneous complaint of fever to health workers, which increased both correct treatment and overtreatment by 72 and 210%, respectively (p?
机译:背景技术需要及时有效的病例管理以减少疟疾的发病率和死亡率。但是,疟疾的诊断和治疗是一个多步骤的过程,在许多情况下仍然存在问题,导致错过有效治疗以及过度治疗无疟疾患者的机会。方法在2011年底广泛推广疟疾快速诊断测试(RDT)之前,在马拉维进行了一项全国性,横断面,复杂样本的卫生机构调查,以评估患者,卫生工作者和卫生机构多元Poisson回归模型与疟疾病例管理质量相关的高水平因素。结果在接受调查的2019名患者中,有34%在参考血涂片上已确认疟疾定义为发烧和寄生虫血症。已确诊疟疾的患者中有67%正确地接受了一线抗疟处方,大多数情况是由于漏诊而导致治疗不正确;未确诊疟疾的患者中有31%用抗疟药过度治疗。卫生工作者未对超过四分之一的患者进行发烧或发烧史评估。正确控制疟疾病例最重要的决定因素是患者水平的临床症状,例如卫生工作者自发发烧,这分别使正确治疗和过度治疗分别增加了72%和210%(p?<0.0001)。咳嗽的投诉与正确治疗疟疾的可能性降低了27%(p?=?0.001)。较低级别的卫生工作者干部为患者开出抗疟药的可能性更高,从而增加了正确治疗和过度治疗的可能性,但是没有其他卫生工作者或卫生机构一级的因素与病例管理质量显着相关。结论引入RDT具有改善马拉维疟疾病例管理的潜力,但是卫生工作者必须系统地评估所有患者的发烧情况,然后进行相应的测试和治疗,否则,尽管有更好的控制方法,疟疾控制计划仍可能会错过大幅改善疟疾病例管理的机会。诊断工具。

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