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Benign Ancient Schwannoma of the abdominal wall: An unwanted birthday present

机译:腹壁良性古代神经鞘瘤:多余的生日礼物

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Background There has been a recent growth in the use of whole body Computerised Tomography (CT) scans in the private sector as a screening test for asymptomatic disease. This is despite scant evidence to show any positive effect on morbidity or mortality. There has been concern raised over the possible harms of the test in terms of radiation exposure as well as the risk and anxiety of further investigation and treatment for the large numbers of benign lesions identified. Case Presentation A healthy 64 year old lady received a privately funded whole body CT scan for her birthday which revealed an incidental mass in the right iliac fossa. This was investigated with further imaging and colonoscopy and as confident diagnosis could not be made, eventually excised. Histology demonstrated this to be a benign ancient schwannoma and we believe this to be the first reported case of an abdominal wall schwannoma in the English literature Conclusions Ancient schwannomas are rare tumours of the peripheral nerve sheaths more usually found in the head, neck and flexor surfaces of extremities. They are a subtype of classical schwannomas with a predominance of degenerative changes. Our case highlights the pitfalls of such screening tests in demonstrating benign disease and subjecting patients to what turns out to be unnecessary invasive investigation and treatment. It provides evidence as to the consequences of the large number of false positive results that are created by blind CT scanning of asymptomatic patients i.e. its tendency to detect pseudodiesease rather than affect survival rates. Should the number of scans increase there may be an unnecessary burden on NHS resources due to the large numbers of benign lesions picked up, that are then referred for further investigation.
机译:背景技术最近,在私营部门中使用全身计算机断层扫描(CT)扫描作为无症状疾病的筛查测试的趋势正在增长。尽管缺乏证据显示对发病率或死亡率有任何积极影响,但这仍然没有。对于放射线暴露的测试可能带来的危害以及对大量已确定的良性病变的进一步研究和治疗的风险和忧虑,引起了人们的关注。病例介绍一位健康的64岁女士在她生日那天接受了私人资助的全身CT扫描,结果发现右窝有一个偶然的肿块。通过进一步的影像学检查和结肠镜检查对此进行了调查,由于无法做出确定的诊断,最终将其切除。组织学证明这是一种良性的古代神经鞘瘤,我们相信这是英国文献中首例报道的腹壁神经鞘瘤病例。结论结论古代神经鞘瘤是一种罕见的周围神经鞘瘤,多见于头,颈和屈肌表面四肢。它们是典型的神经鞘瘤的亚型,具有变性的优势。我们的案例凸显了此类筛查测试在证明良性疾病并使患者接受不必要的侵入性检查和治疗方面的陷阱。它为无症状患者的盲CT扫描所产生的大量假阳性结果的后果提供了证据,即其倾向于检测假性疾病而不影响存活率的趋势。如果扫描次数增加,由于良性病变的数量很多,可能会给NHS资源带来不必要的负担,然后将其转交给进一步调查。

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