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A multicenter, prospective study evaluating the impact of the clinical pharmacist-physician counselling on warfarin therapy management in Lebanon

机译:一项多中心的前瞻性研究,评估了临床药剂师-医师咨询对黎巴嫩华法林治疗管理的影响

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Health care professionals (HCP) are known key elements of effective patient’s counselling and education. For patients taking warfarin, education about the dose, side effects, and toxicity is clearly identified as a cornerstone of achieving improved health and quality of life. The study objective was to evaluate the patients’ knowledge about warfarin and assess the impact of the health care professionals’ counselling in enhancing patients’ knowledge in achieving warfarin therapeutic outcomes. A six-month prospective multicentered study was conducted in three hospitals, enrolling 300 patients admitted to the cardiac care unit and internal medicine departments. Patients’ warfarin knowledge and INR levels were assessed before and after the clinical pharmacist counselling. The main therapeutic outcome was the impact of the clinical pharmacist-physician counselling on improving patient’s education and achieving therapeutic INR level. A higher mean knowledge about warfarin score was found after counselling as compared to before counselling (4.82 vs 13.2; p?
机译:医疗保健专业人员(HCP)是有效进行患者咨询和教育的关键要素。对于服用华法令的患者,有关剂量,副作用和毒性的教育显然被确定为改善健康和生活质量的基石。该研究的目的是评估患者对华法林的了解,并评估医护人员的咨询对增强患者对华法林治疗效果的了解的影响。在三家医院进行了为期六个月的前瞻性多中心研究,招募了300名进入心脏护理部门和内科治疗的患者。在临床药剂师辅导之前和之后评估患者的华法林知识和INR水平。主要的治疗结果是临床药剂师/医师咨询对改善患者的教育程度和达到治疗性INR水平的影响。与咨询前相比,咨询后发现对华法林评分的平均知识更高(4.82 vs 13.2; p <0.001)。同样,药物剂量(1.05比1.88),药物毒性(0.41比1.92),药物和食物-药物相互作用(0.02比1.89),治疗性INR和一般药物知识得分(2.66比4.68)显着更高。与咨询前相比(所有变量的p <0.001)。在咨询之前/之后达到治疗性INR水平的患者百分比分别为37.2%和74.4%(p <0.001)(p <0.001)。根据研究结果,HCP在增强患者对影响华法林治疗结局的因素的了解中起着重要作用。这项研究强调了建立和发展适当使用华法林的策略的必要性。

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