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Translation of SBGN maps: Process Description to Activity Flow

机译:SBGN映射的翻译:过程描述到活动流

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Background The Systems Biology Graphical Notation (SBGN) provides standard graphical languages for representing cellular processes, interactions, and biological networks. SBGN consists of three languages: Process Descriptions (PD), Entity Relationships (ER), and Activity Flows (AF). Maps in SBGN PD are often large, detailed, and complex, therefore there is a need for a simplified illustration. Results To solve this problem we define translations of SBGN PD maps into the more SBGN AF maps. We present a template-based translation which allows the user to focus on different aspects of the underlying biological system. We also discuss aspects of laying out the AF map and of interactive navigation between both the PD and the AF map. The methods developed here have been implemented as part of SBGN-ED ( http://www.sbgn-ed.org webcite ). Conclusions SBGN PD maps become much smaller and more manageable when translated into SBGN AF. The flexible translation of PD into AF and related interaction methods are an initial step in translating the different SBGN languages and open the path to future research for translation methods between other SBGN languages.
机译:背景技术系统生物学图形符号(SBGN)提供了用于表示细胞过程,相互作用和生物网络的标准图形语言。 SBGN由三种语言组成:流程描述(PD),实体关系(ER)和活动流(AF)。 SBGN PD中的地图通常较大,详细且复杂,因此需要简化的插图。结果为了解决此问题,我们将SBGN PD映射转换为更多的SBGN AF映射。我们提出了一个基于模板的翻译,它允许用户专注于基础生物学系统的不同方面。我们还将讨论布局AF地图以及在PD和AF地图之间进行交互式导航的各个方面。此处开发的方法已作为SBGN-ED(http://www.sbgn-ed.org webcite)的一部分实现。结论转换为SBGN AF后,SBGN PD映射变得更小,更易于管理。将PD灵活地转换为AF和相关的交互方法是翻译不同SBGN语言的第一步,并为其他SBGN语言之间的翻译方法的未来研究开辟了道路。

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