Anterior lens capsule and epithelium thickness measurements using spectral-domain optical coherence tomography

摘要

Background To investigate the anterior lens capsule and epithelium thickness (defined as anterior lens capsular complex: ALCC) in normal Chinese subjects using spectral-domian optical coherence tomography (SD-OCT) and examine the factors that may influence the ALCC, such as age, gender, pupil diameter (PD) and signal strength index (SSI). Methods A prospective observational case series. One-hundred-thirty-four normal subjects (134 eyes) were included. The ALCCs were determined manually via SD-OCT. Using the pupil center as a reference position, the central ALCC (CALCC), nasal 1-mm ALCC (NALCC), temporal 1-mm ALCC (TALCC) and PD were measured manually. Results The mean CALCC, NALCC and TALCC were 33?±?6?μm, 36?±?7?μm and 34?±?6?μm, respectively. The NALCC was significantly thicker than the CALCC ( P P P =?0.013). Age was positively correlated with the CALCC ( r =?0.292, P r =?0.400, P r =?0.521, P Conclusions The SD-OCT can be used to demonstrate the ALCC thickness, and age is positively correlated with the ALCC in the central, nasal and temporal sides.